Linzidomin

Linzidomin
Klinički podaci

Drugs.com	Monografija
Identifikatori
ATC kod	C01DX18 (WHO)
PubChem	CID 5219
UNII	5O5U71P6VQ^Y
KEGG	D07161^Y
Sinonimi	SIN-1
Hemijski podaci
Formula	C₆H₁₀N₄O₂
Molarna masa	170,169
SMILES N=C1O[N-][N+](=C1)N2CCOCC2
InChI InChI=1S/C6H10N4O2/c7-6-5-10(8-12-6)9-1-3-11-4-2-9/h5,7H,1-4H2^Y Key:FKDHHVKWGRFRTG-UHFFFAOYSA-N^Y

Linzidomin je organsko jedinjenje, koje sadrži 6 atoma ugljenika i ima molekulsku masu od 170,169 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	4
Broj donora vodonika	1
Broj rotacionih veza	1
Particioni koeficijent^[1] (ALogP)	-0,8
Rastvorljivost^[2] (logS, log(mol/L))	2,4
Polarna površina^[3] (PSA, Å²)	69,6

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.